Bioreactor Sparger

Yakajairika Sparge Tube Dhizaini Idea

Madiki bioreactors anogona kunyatso govera okisijeni uye kubvisa kabhoni dhaibhoni pasina nebulizer. Nekudaro, matanho aya haashande kune akakura bioreactors, sezvo yakaderera nzvimbo kusvika kuvhoriyamu reshiyo inotungamira kuunganidzwa kwekabhoni uye inodzivirira kupinda kweokisijeni. Nokudaro, nebulizers inofanirwa kuiswa kweokisijeni uye kubvisa carbon dioxide.

Masisitimu ane madiki uye mahombe nebulizer anowanzo batsira nekuti anogona kusangana akasiyana maitiro ekuda. Semuyenzaniso, hombe nebulizers anogadzira mabhuru akakura anonyatso bvisa yakanyungudika CO 2 kubva mugadziriso, asi mabhuru mahombe anoda kubvongodzwa kwakasimba kuti aaputse uye kuburitsa okisijeni.

Kunyangwe izvi zvichigona kushanda nemasero kutonhora-kushivirira maseru, kubvongodza kunogona kukuvadza mamwe maseru akatetepa. Muzviitiko izvi, yakaderera-powered macro-distributor inogona kushandiswa kutanga kubvisa CO 2 uyezve micro-distributor munhevedzano kuti ibudise mabhuru maduku anopa oxygen zvakanyanya.

Sintered Porous Metal Sparger Makes

Interfacial Area Inowedzera Asi Bubble Saizi Inodzikira

Dambudziko: Bubble Hunhu Sarudza O2 Yekufambisa uye CO 2 Vapor Kubvisa Matengo

Kuumbwa kwebubble uye saizi zvinonyanya kukanganisa mafambisirwe okisijeni mukati meiyo bioreactor. Bubble maitiro anonyanya kupesvedzerwa nehukuru hwepore uye kugovera, zvinhu zvekugovera, chiyero chekuyerera, mvura uye gasi zvivakwa, uye kudzvanywa. Semuyenzaniso, ma micro sprayers anoburitsa madiki, mabhururu akatenderera, ukuwo masprayers mahombe anoburitsa mabhuru akakura zvishoma uye asina kufanana.

Micro spargers inogadzira micron-saizi uye spherical mabhubhu, uye kushushikana kwepamusoro ndiro simba guru pavanenge vachipfuura nepakati peiyo bioreactor. Ivo, saka, vane nguva refu yekugara mu reactor, iyo inovandudza okisijeni, asi haina kukodzera kubvisa carbon dioxide kubva mutsika.

Mahombe nebulizer anoburitsa mabubbles ane avhareji yedhayamita ye1-4 mm, uko kudzvanya kwepamusoro uye kubhuroka mumuto zvinosangana kuti zvipe chimiro nekufamba kwavo. Mafuro aya ane nguva pfupi yekugara asi haanyanyi kunyungudika pane mabhuru madiki. Nekudaro, madiki spargers anogona zvakare kuburitsa akakura asymmetric bubble, ane inertial masimba anotonga maitiro avo. Aya mabhuru anogona kuputika zviri nyore pasina kunyungudika kana kubvisa CO2.

Chimiro uye hukuru hwemabhubhu zvinotarisa kuwanda kweshear stress iyo sero ichasangana nayo, kushanda kwekubvisa CO 2 kubva muhurongwa, uye chiyero chekutamisa okisijeni yesero. Naizvozvo, zvakakosha kukwidziridza iyo bioreactor nebulizer kuti ive nechokwadi chekuti mabhuru eokisijeni akaenzana muhukuru uye kugovera uye haakuvadze maseru.

Mhinduro: Shandisa Yakasimba Kugadzira Hunhu Kudzora kweHENGKO Bioreactor Sparger

HENGKO ane anopfuura makore makumi maviri echiitiko chekugadzira uye kugadzira sintered sparger. Yedu simbi isina tsvina sparger mhedzisiro yemakumi einjiniya ayo agara achinatsiridza nzira yekugadzira kugadzira ichi chemhando yepamusoro chigadzirwa chine maunifomu pores uye, nekudaro, saizi yebubble yunifomu yakaburitswa mubioreactor. Yedu porous spagers inokurudzirwa kuti ishandiswe ine yakaderera-kuyerera mass flow controllers.

Nzira yekushandisa:Iyo yakaderera-yekuyerera mass flow controller zvishoma nezvishoma inopinza oxygen mu porous sparger. Maspager haabudisi gasi pakarepo. Pane kudaro, kudzvinyirira kunowedzera zvishoma nezvishoma kusvikira nzvimbo yakaoma yasvika, panguva iyo mabhubhu anosunungurwa zvinyoronyoro mubioreactor.

Uchishandisa nzira iyi yekuyerera, mwero weokisijeni wehuwandu hwekuyerera unogona kugadziridzwa kudzora kuburitswa kwemabhuru mu bioreactor. Maburi emu sparger madiki zvekuti mabubbles achaita seasingafungire. Naizvozvo, iyi bioreactor sparging tekinoroji inokwidziridzwa muhukuru hwengarava, ine mwero wekufambisa okisijeni wakaenzana nechiyero chekuyerera kwegasi.

Mibvunzo Nezve Bioreactor Sparger

1. Chii chinonzi Sparger muBioreactor?

Muchidimbu, sparger mudziyo unoshandiswa mubioreactor kuunza magasi, senge okisijeni kana mweya, mukati memvura yepakati. Basa guru re sparger nderokupa oxygen kune microorganisms mu bioreactor, iyo inofanirwa pakukura kwavo uye metabolism.

Iyo Sparger mune bioreactor inoshandiswa kuwedzera magasi akadai seokisijeni, mweya, kana mamwe magasi anodiwa pakukura uye metabolism yema microorganisms. Iyo okisijeni inopihwa kune ma microorganisms kuburikidza neSparger, iyo inobatsira kuchengetedza yakanyungudika mazinga eokisijeni mukati memvura yemvura. Iwo akanyungudika eokisijeni mazinga akakosha parameter yekutarisa uye kudzora panguva yebioprocess sezvo ichikanganisa zvakananga kukura uye metabolism yema microorganisms.

Iyo Sparger yakagadzirirwa kuunza gasi mukati memvura yepakati nenzira inodzorwa, senge kuburikidza ne porous zvinhu kana machubhu. Iyo Sparger inogona kuwanikwa pasi kana kumusoro kweiyo bioreactor, zvichienderana nekugadzirwa kweiyo bioreactor uye rudzi rwema microorganisms anoshandiswa. Iyo Sparger inogona kugadziridzwa kuti ipe iyo inodiwa yekufambisa okisijeni uye kuchengetedza yakakodzera yakanyungudika oksijeni mwero mukati.

Iyo Sparger inoitawo basa rakakosha mukuchengetedza huwandu hwekutamisa chiyero, iyo chiyero icho okisijeni inotamiswa kubva pachikamu chegasi kuenda kuchikamu chemvura. Huwandu hwekutamisa huwandu hunogona kukanganiswa nezvinhu zvakaita sehukuru uye chimiro cheiyo bioreactor, mhando uye kusungirirwa kwehutachiona, uye tembiricha uye pH yepakati. Iyo Sparger inogona kushandiswa kudzora zvinhu izvi uye kukwidziridza huwandu hwekutamisa mwero, izvo zvakakosha pakubudirira kweiyo bioprocess.

Muchidimbu, basa guru re sparger mune bioreactor kupa okisijeni kune ma microorganisms ari mukati memvura yemvura, iyo inodiwa mukukura kwavo uye metabolism, uye kuchengetedza iyo yakakodzera yakanyungudika mazinga eokisijeni uye kuwanda kwekutamisa mwero, izvo zvakakosha kubudirira kweiyo bioprocess.

Chii chinorehwa naSparger?

A sparger mudziyo unoshandiswa kupinza gasi mumvura. Iyo inowanzoshandiswa mune bioreactors, ari midziyo yakasarudzika inoshandiswa kurima tupukanana kana maseru pasi pemamiriro akadzorwa.

Chii chinonzi Basa reSparger?

Basa re sparger nderokupa oxygen kana imwe gasi kune bioreactor kuitira kutsigira kukura uye metabolism yemasero kana microorganisms.

Chii chinonzi Sparger muBioreactor Tsanangura Mhando dzayo?

Kune akati wandei marudzi e spargers anogona kushandiswa mune bioreactor. Izvi zvinosanganisira bubble spargers, izvo zvinogadzira kuenderera kunoramba kuchiyerera kwemafuru mumvura, uye kupfapfaidza spargers, iyo inoparadzira gasi semhute yakanaka. Dzimwe mhando dzema spargers dzinosanganisira porous spargers uye hollow-fiber spargers.

Sparger Iri kupi muBioreactor?

Iyo sparger inowanzo kuwanikwa pazasi peiyo bioreactor, iyo inogona kunyatso kusanganisa gasi nemvura. Mukukura-kuvirisa maitiro, bubble spargers inowanzoshandiswa sezvo iri nyore uye isingadhure kushanda.

Ndeupi Rudzi rweSparger Inonyanya Kushandiswa muMakuru Scale Kuvirisa?

Mukukura-kuvirisa maitiro, bubble spargers inowanzoshandiswa sezvo iri nyore uye isingadhure kushanda. Bubble sparger ine chubhu kana pombi ine maburi madiki kana mitsetse inopinzwa iyo gasi mumvura. Iyo gasi inoyerera nemumakomba kana maslots uye inoumba inoenderera inoyerera yemabhuru mumvura. Bubble spargers inoshanda pakupa huwandu hukuru hwegasi kune bioreactor uye inogona kugadziridzwa zviri nyore kudzora kuyerera kwegasi. Iwo zvakare ari nyore kuchenesa nekuchengetedza. Nekudaro, mabubble spargers anogona kugadzira mabhuru akakura izvo zvingave zvisingaite pakupa nzvimbo yakakwirira yepamusoro kuti maseru kana ma microorganisms asangana negasi. Mune zvimwe zviitiko, sparger kana imwe mhando ye sparger inogona kunge yakakodzera kune imwe nzira yekuvirisa.

Chii Chaunoda Kuziva NezveSparger System?

Pane zvinhu zvakati wandei zvaunofanira kufunga nezvazvo paunenge uchishandisa sparger system mune bioreactor. Izvi zvinosanganisira:

1. Calibration:Izvo zvakakosha kuti unyatso kuenzanisa mwero wekuyerera kwegasi riri kuunzwa mubioreactor. Izvi zvichava nechokwadi chekuti huwandu hwakakodzera hwegasi huri kupihwa kumaseru kana tupukanana uye kuti iyo oxygen yekuisa mubioreactor iri mukati meinodiwa renji.

2. Oxygen concentration:Iko kusanganiswa kweokisijeni mu bioreactor kunofanirwa kutariswa nguva nenguva kuti ive nechokwadi chekuti iri mukati meiyo inodiwa mutsara wemasero kana tupukanana tudiki turi kurimwa. Kana iyo oxygen concentration yakanyanyisa kana yakaderera, inogona kukanganisa kukura uye metabolism yemasero kana tupukanana.

3. Kudzivirira kusvibiswa:Zvakakosha kuve nechokwadi kuti sparger uye nzvimbo yakapoteredza yakanyatsocheneswa uye inochengetwa kudzivirira kusvibiswa kwebioreactor. Izvi zvinogona kusanganisira kugara uchitsiva magasi sefa uye kuchenesa sparger nenzvimbo dzakatenderedza nemishonga inouraya utachiona yakakodzera.

4. Kuyerera kwegasi:Kuyerera kwegasi kunofanirwa kugadziridzwa sezvinodiwa kuchengetedza iyo inodiwa oxygen concentration mu bioreactor. Mwero wekuyerera ungangoda kuwedzerwa kana kudzikiswa zvichienderana nekudiwa kweokisijeni kwemaseru kana tupukanana uye chiyero chekushandisa gasi.

5. Maintenance:Kugara uchichengetedza sparger system kwakakosha kuve nechokwadi kuti iri kushanda nemazvo uye nemazvo. Izvi zvinogona kusanganisira kuongorora kana pakadonhera, kutsiva nhengo dzakasakara kana dzakakuvara, uye kuchenesa sparger nenzvimbo dzakapoteredza sezvinodiwa.

2. Basa guru reSparger muBioreactor?

Basa guru re sparger mune bioreactor kuunza magasi, akadai seokisijeni kana mweya, mukati memvura yepakati. Izvo zvinodiwa pakukura uye metabolism yezvipembenene mu bioreactor, sezvo zvinoda oxygen yekufema. Iyo Sparger inobatsira kupa ma microorganisms neokisijeni inodiwa uye kuchengetedza akakodzera oksijeni mwero mu bioreactor kutsigira kukura kwavo uye metabolism, izvo zvakakosha pakubudirira kweiyo bioprocess.

A: Kuunza magasi:Basa guru re sparger mune bioreactor kuunza magasi, akadai seokisijeni kana mweya, mukati memvura yepakati. Inobatsira kupa ma microorganisms neokisijeni inodiwa yekukura uye metabolism.

B: Kuchengeta mazinga eokisijeni akanyungudika:Iyo Sparger inobatsira kuchengetedza yakanyungudika okisijeni mazinga mune yemvura yepakati. Aya mazinga akakosha paramende yekutarisa uye kutonga panguva yebioprocess sezvo ichikanganisa zvakananga kukura uye metabolism yema microorganisms.

C: Kudzora mwero wekufambisa gasi:Iyo Sparger yakagadzirirwa kuunza gasi mukati memvura yepakati nenzira inodzorwa. Iyo Sparger inogona kugadziridzwa kuti ipe iyo inodiwa yekufambisa okisijeni uye kuchengetedza yakakodzera yakanyungudika oksijeni mwero mukati.

D: Kuchengeta mwero wekutamisa huwandu:Iyo Sparger inoitawo basa rakakosha mukuchengetedza huwandu hwekutamisa chiyero, iyo chiyero icho okisijeni inotamiswa kubva pachikamu chegasi kuenda kuchikamu chemvura.

E: Kugadzirisa bioprocess:Iyo Sparger inogona kushandiswa kudzora zvinhu zvakaita sehukuru uye chimiro cheiyo bioreactor, mhando, uye kusungirirwa kwehutachiona, uye tembiricha uye pH yepakati, kukwirisa bioprocess.

F: Kupa Kusanganisa:Spargers inobatsirawo kugadzira musanganiswa wakafanana wemvura uye gasi nekupa kusanganisa chiitiko. Inobatsira mukupa ma microorganisms nenzvimbo yakafanana.

3. Mhando dzeSparger mune bioreactor?

Mhando dzinoverengeka dze spargers dzinosanganisira porous dombo spagers akagadzirwa ne porous material senge ceramic kana sintered simbi uye bubble column spargers, anoshandisa akatevedzana machubhu kana nozzles kupinza gasi mumvura.

Mhando dzinoverengeka dzesparger dzinogona kushandiswa mune bioreactor, kusanganisira:

1. Masipari ematombo ane porous:Izvi zvinogadzirwa ne porous zvinhu zvakaita seceramic kana sintered simbi uye inoiswa pazasi peiyo bioreactor. Ivo vanopa nzvimbo yakakura yepamusoro yekufambisa gasi uye inowanzoshandiswa mune madiki-scale bioreactors.

2. Mapupu mbiru spargers:Aya anoshandisa nhevedzano yemachubhu kana nozzles kupinza gasi mumvura. Inogona kuiswa pazasi kana pamusoro peiyo bioreactor uye inowanzoshandiswa mune yakakura-scale bioreactors.

3. Ring sparger:Aya anoiswa pazasi peiyo bioreactor uye anoshandisa chimiro chakaita serin'i kugadzira mabhuru uye kupa mweya wekufambisa.

4. Micro-bubble Sparger:Izvi zvakagadzirirwa kugadzira mabhuru madiki anopa huwandu hwekufambisa okisijeni uye anoshandiswa zvakanyanya muhukuru-hukuru, hwakanyanya density bioreactors.

5. Jet sparger:Aya anoshandisa seti yezviputi kupinza gasi mumvura. Inogona kuiswa pasi kana kumusoro kweiyo bioreactor uye inowanzoshandiswa mu-high-shear bioreactors.

6. Paddlewheel sparger:Rudzi urwu rweSparger rinoshandisa vhiri repaddle rinotenderera kugadzira mabhubhu uye kupa kufambisa kweokisijeni. Inowanzoshandiswa mukuvirisa maitiro.

Aya ndiwo mamwe emhando dzinowanzo shandiswa sparger mune bioreactors, uye sarudzo yeSparger inoenderana nehukuru, mhando, uye dhizaini yebioreactor uye chaiyo bioprocess iri kushandiswa.

4. Maitiro ekuseta Sparging Levels muBioreactor?

Iyo sparging level mubioreactor inowanzoiswa zvichienderana nekudiwa kweokisijeni kwema microorganisms, chiyero chekufambisa gasi, uye mwero wekuyerera kwegesi. Zvinhu zvinogona kukanganisa mwero we sparging zvinosanganisira saizi uye chimiro cheiyo bioreactor, mhando uye kusungirirwa kwema microorganisms, uye tembiricha uye pH yepakati.

5. Basa reSparger muBioreactor?

Basa re sparger mubioreactor kuunza magasi, senge okisijeni kana mweya, mukati memvura yepakati kuti isangane nezvinodiwa neokisijeni yehudiki. Izvo zvakakosha pakukura uye metabolism yema microorganisms uye, pakupedzisira, kuti bioprocess ibudirire.

Iyo Sparger inobatsira kupa hutachiona neokisijeni inodiwa yekukura uye metabolism. Inobatsira kuchengetedza iyo yakanyungudika okisijeni mazinga mune yemvura svikiro, ayo akakosha ma paramita ekutarisa uye kudzora panguva yebioprocess sezvo anokanganisa zvakananga kukura uye metabolism yema microorganisms.

Iyo Sparger yakagadzirirwa kuunza gasi mukati memvura yepakati nenzira inodzorwa, senge kuburikidza ne porous zvinhu kana machubhu. Iyo Sparger inogona kuwanikwa pasi kana kumusoro kweiyo bioreactor, zvichienderana nekugadzirwa kweiyo bioreactor uye rudzi rwema microorganisms anoshandiswa. Iyo Sparger inogona kugadziridzwa kuti ipe iyo inodiwa yekufambisa okisijeni uye kuchengetedza yakakodzera yakanyungudika oksijeni mwero mukati.

Iyo Sparger inoitawo basa rakakosha mukuchengetedza huwandu hwekutamisa chiyero, iyo chiyero icho okisijeni inotamiswa kubva pachikamu chegasi kuenda kuchikamu chemvura. Huwandu hwekutamisa huwandu hunogona kukanganiswa nezvinhu zvakaita sehukuru uye chimiro cheiyo bioreactor, mhando uye kusungirirwa kwehutachiona, uye tembiricha uye pH yepakati. Iyo Sparger inogona kushandiswa kudzora zvinhu izvi uye kukwidziridza huwandu hwekutamisa mwero, izvo zvakakosha pakubudirira kweiyo bioprocess.

Sparger inobatsirawo kugadzira homogenous musanganiswa wemvura uye gasi nekupa musanganiswa chiitiko. Inobatsira mukupa ma microorganisms nenzvimbo yakafanana.

Muchidimbu, basa re sparger mune bioreactor kupa okisijeni kune ma microorganisms ari mukati memvura yemvura, iyo inodiwa mukukura kwavo uye metabolism, uye kuchengetedza iyo yakakodzera yakanyungudika mazinga eokisijeni uye kuwanda kwekutamisa mwero, izvo zvakakosha kune kubudirira kweiyo bioprocess. Iyo inobatsirawo kugadzira homogenous musanganiswa uye inopa musanganiswa chiito kune yemvura yepakati.

Imhando ipi yeBioreactor Sparger yaunoda kushandisa kana Kugadzirisa?

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